We present new petrological data of the Titaros ophiolite complex and discuss their significance for the Alpine geodynamic evolution in the Pelagonian realm. There are two Alpine high-P metamorphic stages. The first stage, at pressures between 0.8-1.4 GPa and minimum temperatures 570-610 ºC occurred in late Jurassic/early Cretaceous and is associated with the obduction of the ophiolite complexes onto the Pelagonian crust. At this stage the Titaros ophiolite was subducted together with crustal rocks of the Pelagonian zone as a result of tectonic erosion of the ophiolite margin. The second stage occurred in the Eocene at much lower temperatures (about 400 ºC and minimum pressure ~0.7 GPa). It is interpreted to reflect the final closure of the Vardar-Axios ocean and collision/underthrusting of the Apulia microcontinent under Europe.